Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.

Whole-body glucose turnover during clamps tended to decrease by 10% in male Exoc5 -SMKO mice compared with male controls, similarly to whole-body glycogen synthesis, although the differences did not reach statistical significance ( p = 0.0851 and p = 0.0587, respectively) ( Fig. 4 , C and D ).

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