Are psychiatric disorders risk factors for COVID-19 susceptibility and severity? a two-sample, bidirectional, univariable, and multivariable Mendelian Randomization study.

Transl Psychiatry · 2021 · PMC8027711 · PMID 33833219

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At a nominally significant p value threshold ( p < 0.05), we detected causal effects of genetic liability to SCZ on very severe COVID (A2) and COVID-19 susceptibility (D1), of genetic liability to BIP on severe and very severe COVID-19 (A1 and B2), and of genetic liability to AD on COVID-19 susceptibility (C1 and D1, Supplementary Table 3A ).

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