Inflammatory Foreign Body Response Induced by Neuro-Implants in Rat Cortices Depleted of Resident Microglia by a CSF1R Inhibitor and Its Implications.

Interestingly, during the first 3 days post-PPMP implantation, the NFI values in the first shell (0–25 μm from the electrode’s surface) showed a trend toward reduction in both the control and PLX5622 pre-fed rats ( Figure 9A ).

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