(+)-[<sup>18</sup>F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand-results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer's disease and healthy controls.

Eur J Nucl Med Mol Imaging · 2021 · PMC8036219 · PMID 32935187

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

1.19 ± 0.06, p = 0.03) and a further region showed a trend: left frontal cortex (1.08 ± 0.03 vs. 1.11 ± 0.06, p = 0.06), whereas left mesial temporal cortex survived correction for multiple testing.

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a trend towards significanceno p-value reported

However, in two of the 10 a-priori defined regions, the p values showed a trend towards significance.

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