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Feedback Regulation of <i>O</i>-GlcNAc Transferase through Translation Control to Maintain Intracellular <i>O</i>-GlcNAc Homeostasis.

Int J Mol Sci · 2021 · PMC8037101 · PMID 33801653

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RT-qPCR results revealed that in CL1-5 cells treated with the OGA inhibitor TMG to increase O -GlcNAc levels, OGA mRNA expression was significantly increased as compared to that of untreated cells ( Figure 2 A), although the changes of OGA mRNA level in A549 cells did not reach statistical significance.

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