According to Kaplan–Meier curve analysis and the log-rank test, rs2230054 was significantly associated with the time from initial diagnosis to the diagnosis of metastatic disease ( p = 0.05), although the association with rs699947 did not reach statistical significance ( p = 0.07) ( Figure S3 ). 2.8.
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Biomarkers Associated with Regorafenib First-Line Treatment Benefits in Metastatic Colorectal Cancer Patients: REFRAME Molecular Study.
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