In a small study of ambulatory boys with DMD, ACE-031, a fusion protein of ActRIIB and IgG1-Fc only showed a trend toward increasing LBM, BMD and maintenance of the 6-min walk test (6MWT) ( Campbell et al., 2017 ).
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Deciphering Myostatin's Regulatory, Metabolic, and Developmental Influence in Skeletal Diseases.
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