While some benefit appeared to be present in observational studies [ 16 ], according to a recent randomized study [ 17 ] and a meta-analysis [ 5 ] a significant benefit appears to be missing or only marginally significant for recurrent strokes in those patients who were adherent [ 17 ].
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SAS CARE 2 - a randomized study of CPAP in patients with obstructive sleep disordered breathing following ischemic stroke or transient ischemic attack.
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