a near significant trendP = 0.06
In addition, the difference of ORR benefit obtained a near significant trend (OR = 1.92; 95% CI: 0.98–3.72; P = 0.06; and heterogeneity: P = 0.006) ( Fig. 2 C). 3.3 Efficacy outcomes of PD-1 inhibitor versus chemotherapy in ESCC Meanwhile, we analyzed the patients with ESCC to figure out the benefit of anti-PD-1 therapy.