Benchmarking the Human Leukocyte Antigen Typing Performance of Three Assays and Seven Next-Generation Sequencing-Based Algorithms.

A recent study showed that the HLA matched status changed in 29% of pairs after ultra-high resolution (UHR) HLA typing using Pacific Biosciences Single Molecule Real-Time sequencing (Menlo Park, CA, USA), and had significant improved clinic benefit ( 32 ), demonstrating that allele level typing (or all field typing) using NGS or other technologies might be an important trend in the field of HSCT.

also in 1,052 other papers