Among patients with stage II disease, RFS and OS were numerically better in patients receiving adjuvant chemotherapy than in those without adjuvant chemotherapy, although the difference did not reach statistical significance, and adjuvant chemotherapy was marginally associated with favorable RFS in multivariate analysis.
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Adjuvant Chemotherapy for Resected Ampulla of Vater Carcinoma: Retrospective Analysis of 646 Patients.
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The sentences
However, multivariate analysis with prognostic factors showed a marginally significant survival benefit with AC.