The LPS/veh-treated mice WT hippocampus IL-1β group mean tended to be lower than the LPS/sal group mean, but did not reach statistical significance. 4R alone (without LPS) had no effect on TNF-α and IL-1β levels in any of the areas examined and behaved like the saline control.
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4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice.
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