Exercise Diminishes Plasma Neurofilament Light Chain and Reroutes the Kynurenine Pathway in Multiple Sclerosis.

Results Baseline Associations Between pNfL Levels, Cognitive Performance, and KYN Pathway Outcomes Baseline correlations indicated negative associations between pNfL and processing speed (Symbol Digit Modalities Test) ( r = −0.298; p = 0.015) as well as visuospatial memory (Brief Visuospatial Memory Test–Revised) ( r = −0.260, p = 0.035), whereas the association between pNfL and verbal learning (Verbal Learning and Memory Test) did not reach statistical significance ( figure 1 ).

also in 111,027 other papers