Respiratory depression and analgesia by opioid drugs in freely behaving larval zebrafish.

Elife · 2021 · PMC8060028 · PMID 33720013

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showed a trendno p-value reported

CX614 alone did not present higher respiratory rate when compared to control group (p=0.058) but showed a trend toward significance.

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a trend toward significanceno p-value reported

The selective MOR antagonist CTAP (4 μM) did not significantly reverse respiratory rate depression by fentanyl (p=0.077, Figure 3B ), although a trend toward significance was observed.

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