In fact, when THP-1 monocytes were treated with MCP-1 and T 4 , in the presence of the inhibitors of the binding of T 4 to the integrin, RGD, tetrac, or the antibody for the integrin αvβ3, the inhibition of migration was not reverted but showed a trend to a potentiation.
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Inhibition by Thyroid Hormones of Cell Migration Activated by IGF-1 and MCP-1 in THP-1 Monocytes: Focus on Signal Transduction Events Proximal to Integrin αvβ3.
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