Should patients receive consolidation chemotherapy before reduced intensity allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia in first complete remission?

For the consolidation group, patients undergoing alloSCT within 65 days of last chemotherapy showed better RFS compared with those undergoing alloSCT after 65 days (median not reached versus 31 months, respectively, p = 0.078). Although the difference did not reach statistical significance, this finding supports the use of bridging treatment when the expected time lapse between chemotherapy and alloSCT is long.

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