Regarding regulatory markers ICOS and PD1 on CD4+ T-cells and PD-L1 on monocytes, similar to Bregs, the lowest expression was observed in inhibitor patients and the highest expression in ex-inhibitor patients, although these results did not reach statistical significance (PD1: P = 0.89; ICOS: P = 0.66; PD-L1: P = 0.14; Figure 2 ; and Supplemental Table 1, http://links.lww.com/HS/A150 ).
1
0.8900
0.8900