Strengthened luteal phase support for patients with low serum progesterone on the day of frozen embryo transfer in artificial endometrial preparation cycles: a large-sample retrospective trial.

In this study, serum progesterone levels on the FET day, as a categorical variable, were found to be a significant independent prognosticator of clinical pregnancy, while it did not reach statistical significance for the live birth rate.

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The sensitivity analysis showed that the clinical pregnancy rate and live birth rate showed a decreasing trend in the subgroups of cleavage embryo and in the subgroup of single embryo transfer, so we presumed that the endometrium in the context of low progesterone and strengthened LPS was prone to negatively impact on pregnancy potential in the FET cycles with cleavage embryo or single embryo transfer.

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