showed a trendp = 0.083
The Overall Survival Analysis of Candidate Biomarkers in Sera of CCA Patients The overall survival (OS) analysis by the Kaplan–Meier method with a log rank test revealed that only CCA patients with a high level of angiopoietin-2 showed a trend of shorter survival times than those with a low angiopoietin-2 level ( p = 0.083).