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Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19.

J Clin Virol · 2021 · PMC8065244 · PMID 33965698

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In binary logistic regression, absence of HCoV OC43-specific antibodies (adjusted odds ratio (AOR) 2.68 [95% CI 1.09 - 7.05]) and male sex (AOR 2.98 [95% CI 1.38 - 6.63]) were the strongest predictors for critical disease, while age (AOR 1.02 [95% CI 0.99 - 1.04]) and BMI (AOR 1.07 [95% CI 1.00 - 1.16]) did not reach statistical significance in this cohort.

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