Impaired Mitochondrial Function in iPSC-Retinal Pigment Epithelium with the Complement Factor H Polymorphism for Age-Related Macular Degeneration.

Cells · 2021 · PMC8066149 · PMID 33918210

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did not reach statistical significanceno p-value reported

Our results show that under basal conditions, RPE derived from donors with AMD displayed a ~20% reduction in mitochondrial function ( Figure 2 C), which while consistent with our previous report in primary RPE cultures [ 16 ], did not reach statistical significance.

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