While the treatment did not reach statistical significance, the trend certainly indicates that the reduction in bacterial burden can be further enhanced by higher concentration, more frequent dosing, or a refined/optimized RNP0012 next-generation analog or formulation.
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Optimization of 2-Acylaminocycloalkylthiophene Derivatives for Activity against <i>Staphylococcus aureus</i> RnpA.
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