Barely Significant
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The Effectiveness of Probiotic <i>Lactobacillus rhamnosus</i> and <i>Lactobacillus casei</i> Strains in Children with Atopic Dermatitis and Cow's Milk Protein Allergy: A Multicenter, Randomized, Double Blind, Placebo Controlled Study.

Nutrients · 2021 · PMC8066586 · PMID 33916192

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Although the proportion of sensitized children whose SCORAD scores improved from baseline was higher than that in the placebo group (91.2% and 78.4%, respectively), the difference did not reach statistical significance. 3.4.

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an increasing trendno p-value reported
Over the last few decades, there has been an increasing trend in the incidence of AD and food allergy, especially noticeable in highly developed countries, which is associated with a strict hygiene regime, increased use of detergents, low number of children per family, altered nutritional habits, frequent antibiotic therapy, low incidence of infectious diseases, and high numbers of Cesarean sections [ 9 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.