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pH Dependence of <i>T</i><sub>2</sub> for Hyperpolarizable <sup>13</sup>C-Labelled Small Molecules Enables Spatially Resolved pH Measurement by Magnetic Resonance Imaging.

Pharmaceuticals (Basel) · 2021 · PMC8067065 · PMID 33918366

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showed a trendp > 0.05actually significant
While there was no clear dependence between the measured relaxation time constants and the blood pH, measurements with 25 mM hyperpolarized [1- 13 C]pyruvate containing 26.6 μM OX063 radical showed a trend towards a correlation between blood pH ( r = −0.62, p > 0.05) and the T 2 relaxation time constant.

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