clearly significantp = 0.0002
The only positive results were observed in a subgroup with a high rate of spontaneous mutation in CTCs, with a clearly significant RR (83 vs. 33%; p = 0.0002) [ 56 , 70 ]; Olaparib–Abiraterone.
The only positive results were observed in a subgroup with a high rate of spontaneous mutation in CTCs, with a clearly significant RR (83 vs. 33%; p = 0.0002) [ 56 , 70 ]; Olaparib–Abiraterone.
Moreover, in both trials, a positive trend (up to 3-fold) towards improved OS was observed in favour of the ipilimumab arm during the extended follow-up.