The <i>Traf2</i>DNx<i>BCL2-tg</i> Mouse Model of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Recapitulates the Biased IGHV Gene Usage, Stereotypy, and Antigen-Specific HCDR3 Selection of Its Human Counterpart.

Front Immunol · 2021 · PMC8072112 · PMID 33912159

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0.0730

closest p · 1.5× alpha

0.0730

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did not reach statistical significanceP = 0.073so close (0.05 < p ≤ 0.1)

The average length of the UM-CLL/SLL clones developed by the MDR -/- and miR15a/16-1 -/- is slightly longer [12.87 ± 2.17 AAs ( 32 )], but compared to that of the Traf2 DNx BCL2 -tg +/+ UM-CLL/SLL clones these differences did not reach statistical significance ( P = 0.073).

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