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IFITM3 incorporation sensitizes influenza A virus to antibody-mediated neutralization.

J Exp Med · 2021 · PMC8072448 · PMID 33882122

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Of note, the levels of VSV-G in PV VSV were not reduced by IFITM3 expression but the levels of envelope in PV HIV seemed to be reduced, even though this did not reach statistical significance, suggesting that IFITM3-mediated reductions in glycoprotein levels in the virion correlate with a decrease in infectivity.

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