Antiplatelet Therapy Combined with Anastrozole Induces Features of Partial EMT in Breast Cancer Cells and Fails to Mitigate Breast-Cancer Induced Hypercoagulation.

Int J Mol Sci · 2021 · PMC8074114 · PMID 33923802

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Furthermore, AnaAspClop-treated MCF7 cells displayed evidence of a partial EMT, whereas AnaAspClop-treated T47D cells showed a trend towards the acquisition of mesenchymal markers (independent of TGFβ1) and could suggest a role for PAR1-mediated effects [ 34 ] and, furthermore, a more aggressive tumour profile in T47D cells [ 62 ].

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