Low serum klotho concentration is associated with worse cognition, psychological components of frailty, dependence, and falls in nursing home residents.

Sci Rep · 2021 · PMC8079365 · PMID 33907242

Europe PMC DOI

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closest p · 0.2× alpha

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showed a trendp = 0.012actually significant

Regarding cognition, participants with lower s-klotho levels showed a trend toward worse scores in cognition-related tests, with statistical significance in the coding test (WAIS IV), which reflects processing speed (r = 0.256, p = 0.012).

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