ERG responses showed a trend toward increased amplitude and sensitivity of rod oscillatory potentials (OPs) (amacrine cells and ganglion cells) at postnatal week 7 ( Figure S5 B) and a significant increase in the amplitude of cone OPs at postnatal week 10 ( Figure S5 C) in FGF21- vs vehicle-treated P23H mice.
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Retinal glial remodeling by FGF21 preserves retinal function during photoreceptor degeneration.
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