Relevant to this point, Study 3 only showed a trend of EtCO 2 effects on CVR and one possible reason is that participants in Study 3 were all elderly subjects and many of them have commonly vascular risks such as hypertension, hypercholesterolemia, etc. 5.
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The association between BOLD-based cerebrovascular reactivity (CVR) and end-tidal CO<sub>2</sub> in healthy subjects.
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