Global transcriptional downregulation of TREX and nuclear trafficking machinery as pan-senescence phenomena: evidence from human cells and tissues.

Exp Mol Med · 2020 · PMC8080647 · PMID 32859952

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clearly significantno p-value reported

Here, we report a small but clearly significant, decrease in TREXes and NCTFs not only through a variety of aging models but also based on pan-tumor tissue data on aged humans from the GTEx and TCGA databases.

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