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Bexarotene Impairs Cognition and Produces Hypothyroidism in a Mouse Model of Down Syndrome and Alzheimer's Disease.

Front Pharmacol · 2021 · PMC8082148 · PMID 33935706

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In the present study, we found a reduction of Aβ1-40 in the hippocampi of TS animals and a similar tendency in their cortices which did not reach statistical significance.

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