Experimental co-infection of variant infectious bursal disease virus and fowl adenovirus serotype 4 increases mortality and reduces immune response in chickens.

The viral load in the thymus of these two groups gradually increased and peaked at 7 dpi with FAdV-4-HB1501, and the viral copy numbers of the IBDV-FAdV co-infection group trended higher than those of the FAdV-only group, but this difference failed to reach statistical significance (Figure 3 D).

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