These results revealed that there is a clear trend of decreasing in rishirilide B production by the complementation of S. albus × Cos4∆ rslO4 with site-specific mutated rslO4 genes comparing to the wild type.
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Biosynthesis of the Tricyclic Aromatic Type II Polyketide Rishirilide: New Potential Third Ring Oxygenation after Three Cyclization Steps.
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