of marginal significancep = 0.05
Interestingly, patients carrying the UGT1A9 -275A variant allele had lower AUC 0–12h /MPA-D (0.053 [IQR 0.040–0.100] ug*hr/ml/mg/m2) than patients carrying only the UGT1A9 -275T ancestral allele genotype (0.117 [IQR 0.058–0.150]ug*hr/ml/mg/m2) with a difference of marginal significance ( p = 0.05) ( Figure 4 ).