Differences in the OS between the treatment groups did not reach statistical significance in patients with high-volume disease (HR = 0.80; 95% CI = 0.5–1.07) and those with previous docetaxel (HR, 0.90; 95% CI, 0.62–1.31), probably owing to the short follow-up period (median 34 mon); a longer follow-up is necessary for determining the effect of ENZ on OS in this trial.
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Treatment Strategies for Metastatic Castration-Sensitive Prostate Cancer: From "All-Comers" to "Personalized" Approach.
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