Barely Significant
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Effectiveness and safety of dimethyl fumarate in progressive multiple sclerosis.

Mult Scler J Exp Transl Clin · 2021 · PMC8108088 · PMID 33996142

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showed a trendno p-value reported
Conclusion Dimethyl fumarate showed a trend towards reduction in T25FW but no evidence of clinically significant impact on EDSS.

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