Autoantibodies Against the Complement Regulator Factor H in the Serum of Patients With Neuromyelitis Optica Spectrum Disorder.

The mAb IXF9 recognizing an epitope within FH SCR18-19 ( 41 ) inhibited autoantibody binding to FH by ~30% in the case of patients #64, #84 and #113, whereas its slight inhibitory effect did not reach statistical significance in the case of patient #210 ( Figure 5 ).

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