near-significantP = 0.063
Moreover, when selectively analyzing the expression levels of 16 thyroid function and metabolism genes associated with thyroid cell differentiation – the so-called 'thyroid differentiation score' ( Cancer Genome Atlas Research Network 2014 ) – a near-significant ( P = 0.063) difference was found between clusters F and M, with a trend toward higher differentiation in cluster M (Supplementary Fig. 8).