Inhibition-directed multimodal imaging fusion patterns in adults with ADHD and its potential underlying "gene-brain-cognition" relationship.

CNS Neurosci Ther · 2021 · PMC8111492 · PMID 33724699

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0.0670

closest p · 1.3× alpha

0.0670

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The sentences

marginally significantp = 0.067so close (0.05 < p ≤ 0.1)

Genetic effects of NOS1 ex1f‐VNTR genotypes on inhibition and its related brain structural/functional patterns Marginally significant interaction of NOS1 ex1f‐VNTR genotypes (based on the allele counts of 25R) and ADHD diagnosis was found for inhibition function ( F = 2.82, p = 0.067).

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did not reach statistical significanceno p-value reported

In the mediation model of NOS1 ex1f‐VNTR (25R) genotypes, FC, and inhibition, the path from the NOS1 ex1f‐VNTR (25R) genotypes to FC was significant [B = −0.42 (SE = 0.22), p = 0.048], and the path from FC to inhibition was significant [B = 1.28 (SE = 0.39), p = 0.002], but the path from the NOS1 ex1f‐VNTR (25R) genotypes to inhibition did not reach statistical significance.

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