Barely Significant
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uPAR<sup>+</sup> extracellular vesicles: a robust biomarker of resistance to checkpoint inhibitor immunotherapy in metastatic melanoma patients.

J Immunother Cancer · 2021 · PMC8112420 · PMID 33972390

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In addition, uPAR + EVs from melanoma cells and B lymphocytes were nearly statistically significant.

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an increasing trendno p-value reported
In the EVs derived from all cell populations of non-responders, we observed an increasing trend of uPAR + EVs in pretreated patients compared with naive patients, except for EVs from DCs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.