Sodium Monoiodoacetate Dose-Dependent Changes in Matrix Metalloproteinases and Inflammatory Components as Prognostic Factors for the Progression of Osteoarthritis.

Front Pharmacol · 2021 · PMC8113822 · PMID 33995052

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

may not be significantno p-value reported

At the low MIA dose (1 mg), MMP-3 might be involved in the early inflammatory state; however, the OA grade in this group was lower than that in the 2 or 3 mg MIA groups; therefore, the contribution of MMP-3 to OA development may not be significant.

also in 2,774 other papers

did not reach statistical significanceno p-value reported

In the 2 mg MIA group, the Mmp-2 expression level remained elevated on day 28 (similar to the 1 mg MIA group); however, these differences did not reach statistical significance.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.