Consistently, ELISA-based detection revealed lower CXCL-1 protein levels within conditioned medium from LPS-treated Phd2 +/– M1-polarized BMDMs (CM M1 ) compared with medium conditioned with WT or Phd1 –/– BMDMs, albeit this difference did not reach statistical significance ( Supplemental Figure 9B ).
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Inhibition of HIF-prolyl hydroxylases improves healing of intestinal anastomoses.
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