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Pharmacological Management of Painful Peripheral Neuropathies: A Systematic Review.

Pain Ther · 2021 · PMC8119529 · PMID 33145709

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Topical clonidine as add-on, although safe, did not reach statistical significance for the management of painful DPN [ 93 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.