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The bone is the major source of high circulating intact fibroblast growth factor-23 in acute murine polymicrobial sepsis induced by cecum ligation puncture.

PLoS One · 2021 · PMC8121358 · PMID 33989306

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All other pro-inflammatory cytokines also tended to be elevated but due to the high variance within the CLP groups these increases did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.