Receptor-mediated mitophagy regulates EPO production and protects against renal anemia.

Elife · 2021 · PMC8121547 · PMID 33942716

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Furthermore, the level of autophagic genes, such as P62 and LC3-II, showed a trend of reduction in UUO- Fundc1 -/- renal cells, suggesting the accumulation of dysfunctional mitochondria due to deficient autophagy ( Figure 5D ).

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