Atypical E2Fs either Counteract or Cooperate with RB during Tumorigenesis Depending on Tissue Context.

Histopathology analysis revealed that Alb-Rb −/− 7 −/− 8 −/− mice had an increased incidence of malignant liver tumors (hepatocellular carcinomas) compared to Alb-7 −/− 8 −/− mice, although this difference did not reach statistical significance ( Figure 1 D).

also in 111,027 other papers

We observed a slight trend, although not a significant one, of increased thyroid tumor incidence in Rb +/− 7 −/− compared to Rb +/− mice ( Figure 3 D).

also in 4,078 other papers