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Assessment of Betulinic Acid Cytotoxicity and Mitochondrial Metabolism Impairment in a Human Melanoma Cell Line.

Int J Mol Sci · 2021 · PMC8125295 · PMID 34064489

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Moreover, we verified the impact of BA on caspase 3, caspase 8 and Apaf 1 mRNA expression and noticed a downregulation of these markers’ expressions in BA-treated cells (10 μM) as compared to DMSO-treated cells (data not shown) that did not reach statistical significance. 2.5.

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