Tranexamic acid and bleeding in patients treated with non-vitamin K oral anticoagulants undergoing dental extraction: The EXTRACT-NOAC randomized clinical trial.

PLoS Med · 2021 · PMC8128271 · PMID 33939696

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)

In patients who were 75 years or older, there were 24 bleeds in 13/59 (22.0%) patients assigned to TXA and 55 bleeds in 16/51 (31.4%) patients assigned to placebo (rate ratio, 0.35; 95% CI, 0.15 to 0.79), although this interaction did not reach statistical significance ( P = 0.07).

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